Tumours of the brain and presence of antibodies to Toxoplasma gondii

The possible association between prior infection with the protozoan Toxoplasma gondii and development of brain tumours was investigated as part of two Australian population-based case-control studies of adult brain tumours. One study, based in Adelaide, South Australia, collected blood from 73 subjects with glioma, 53 subjects with meninglioma and 3413 controls. The other study, based in Melbourne, Victoria, collected blood from 44 subjects with glioma and 67 controls. All tumours had been verified histologically. IBG antibodies to T. gondii were measured using Enzyme Linked Immunosorbent Assay (ELISA) techniques