Adolescente con esclerosis múltiple de alta actividad

espanolLa esclerosis multiple (EM) es una enfermedad autoinmune del sistema nervioso central (SNC) que se puede presentar de formas muy variadas y progresa generando discapacidad. Menos del 5% de los casos son pediatricos, y aun menos frecuentes son los casos de EM de formas agresivas o de alta actividad. Presentamos el caso de un adolescente de 13 anos que en seis meses tuvo tres brotes, cada vez mas agresivos, con una alta carga de lesion evidenciada en la resonancia magnetica y rapida progresion de su discapacidad. Discutimos la aproximacion diagnostica de la EM en la edad pediatrica, su forma de presentacion y la valoracion de formas de EM con alta actividad. EnglishMultiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) that can occur in many different ways and progresses generating disability. Less than 5% of cases are pediatric, and even less frequent are the cases of MS in aggressive or highly-active forms. We present the case of a 13-year-old boy who in six months had three attacks, each time more aggressive, with a severe disease burden evidenced by MRI and a rapid progression of his disability. We discuss the diagnostic approach of the MS in the pediatric age, its form of presentation and the evaluation of highly active MS forms.