Risk Stratification in Newly Diagnosed Transplant Ineligible Multiple Myeloma

The management of transplant ineligible MM can be challenging due to competing comorbidities and issues with frailty. The choice of regimen, dosing, duration of treatment (continuous versus fixed), management of side effects, and supportive care are all relevant to this patient population. In the present chapter, these aspects of care are summarized considering recent phase III studies as well as frailty assessment models for this patient population.