[162-POS] : Blood pressure criteria for the detection of pre-eclampsia

Objectives Early definition of individuals at risk of pre-eclampsia is desirable for surveillance and treatment. Several studies report criteria for this but there is no general agreement on the various outcomes tested. Methods Hospital records of nulliparous, singleton normal pregnancies ( n  = 100) and those diagnosed with pre-eclampsia ( n  = 109) were obtained from a register at an antenatal health care unit. Data on blood pressure at the regular visits to the unit were collected and analyzed. Results The systolic and diastolic blood pressures were significantly higher at pregnancy week 12 among those who developed pre-eclampsia ( p  = 0.046 and 0.001 resp). An increase in diastolic blood pressure of ⩾15 mmHg occurred more frequently among women with pre-eclampsia. In 93% of the cases this increase was present before and on the same time as the clinical diagnosis of pre-eclampsia was established. Conclusions The results suggest that an increase in diastolic blood pressure of ⩾15 mmHg could be used to identify women at risk of pre-eclampsia and as a selection criterion in magnesium prevention assays. Disclosures R. Rylander: None. M. Bullarbo: None.