MerTK Expression and ERK Activation Are Essential for the Functional Maturation of Osteopontin-Producing Reparative Macrophages After Myocardial Infarction.

Kohsuke Shirakawa,Jin Endo,Masaharu Kataoka,Yoshinori Katsumata,Atsushi Anzai,Hidenori Moriyama,Hiroki Kitakata,Takahiro Hiraide,Seien Ko,Shinichi Goto,Genki Ichihara,Keiichi Fukuda,Tohru Minamino,Motoaki Sano

MerTK Expression and ERK Activation Are Essential for the Functional Maturation of Osteopontin-Producing Reparative Macrophages After Myocardial Infarction.

2020

Kohsuke Shirakawa
Jin Endo
Masaharu Kataoka
Yoshinori Katsumata
Atsushi Anzai
Hidenori Moriyama
Hiroki Kitakata
Takahiro Hiraide
Seien Ko
Shinichi Goto
Genki Ichihara
Keiichi Fukuda
Tohru Minamino
Motoaki Sano

Background We previously reported that osteopontin plays an essential role in accelerating both reparative fibrosis and clearance of dead cells (efferocytosis) during tissue repair after myocardial...

Keywords:

Cell biology
Medicine
Osteopontin
Efferocytosis
Macrophage colony-stimulating factor
Tyrosine kinase
STAT3
MAPK/ERK pathway
STAT protein
MERTK

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