Pharmacokinetics of epinephrine in patients with septic shock: modelization and interaction with endogenous neurohormonal status
2009
Introduction
In septic patients, an unpredictable response to epinephrine may be due to pharmacodynamic factors or to non-linear pharmacokinetics. The purpose of this study was to investigate the pharmacokinetics of epinephrine and its determinants in patients with septic shock.
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