FRI0037 Mer-mediated efferocytosis tempers arthritis by preventing neutrophils to go into secondary necrosis and spill their inflammatory content in the joint

BackgroundRheumatoid arthritis is characterized by an inflammatory response in synovial joints, showing a predominant influx of neutrophils. These cells are cytotoxic and contribute to matrix degradation. In addition, they are implicated as a source of citrullinated auto-antigens, leading to the pro