Five probable factors responsible for COVID-associated mucormycosis outbreak in India.

The second wave of COVID-19 due to Delta (B.1.617.2) variant led to the rapid rise of total coronavirus and COVID-associated mucormycosis cases reported from India. Hence, the current perspective explores the possible causes of rapid upsurge in COVID-associated mucormycosis cases, which was accounted for over 70% of global cases. The five most probable factors associated with the increase of mucormycosis in COVID-19 patients include diabetes mellitus, steroids overdose, high iron levels, immuno-suppression, combined with other possible factors such as unhygienic conditions, prolonged hospitalization, use of ventilators and leaky humidifiers in oxygen cylinders, creates an ideal environment for contracting mucormycosis. However, these cases could be brought down by disseminating simple preventive measures and creating awareness among the medical society and general public on this rare and deadly contagion of COVID-associated mucormycosis. The identification of the early symptoms will help to restrict the spread of lethal fungal diseases. Further, a collaborative team of surgeons, ophthalmologists, physicians, otolaryngologists specialists would be required in the hospital wards to proceed with quick surgeries on severely impacted patients.