Blood pressure lowering effects of Australian canola protein hydrolysates in spontaneously hypertensive rats

Abstract The in vitro and in vivo antihypertensive activities of canola protein hydrolysates and ultrafiltration membrane fractions ( in vitro inhibition of angiotensin converting enzyme (ACE) activity. However, pancreatin hydrolysate was the most effective (63.2%) in vitro renin inhibitor. Membrane fractionation of pancreatin hydrolysate led to a 15% reduction in renin inhibition by the 1–3 kDa peptide fraction. In contrast, ACE and renin inhibitions were significantly (p