Treatment satisfaction with premixed insulin aspart 30%/70% in patients with type 2 diabetes mellitus Satisfacción con el tratamiento con insulina aspart premezclada al 30%/70% en pacientes con diabetes mellitus tipo 2

Treatment satisfaction of diabetic subjects is a key point to ensure treatment compliance due to the characteristics of this chronic disease. The aim of this study was to assess treatment satisfaction with premixed insulin aspart 30%/70% in patients with type 2 diabetes mellitus. In this observational, multicentre and prospective study 1,244 patients with type 2 diabetes mellitus treated with remixed insulin aspart 30%/70%, started within the last 15 days prior to study entry and who had been previously treated with other types of insulin or oral antidiabetic drugs, were included. To measure treatment satisfaction the Diabetes Treatment Satisfaction Questionnaire was used. Results of this questionnaire in visit 1, referred to previous treatment, and visit 3 after 26 weeks of treatment with premixed insulin aspart 30/70% were compared. General treatment satisfaction improved signifi cantly (p <0.0001) at the end of the study (median [interquartilic range] 27 [23;30] in visit 3 versus 17 [12;22] in visit 1). Perception of hyperglycemia (2 [1;3] in visit 3 versus 4 [3;5] in visit 1) also improved at the end of the trial (p <0.0001). No signifi cant differences in perception of hypoglycemia were found (2 [1;3] versus 1 [1;3]). In conclusion, the initiation of a treatment with premixed insulin aspart 30%/70% in subjects with type 2 diabetes mellitus was associated with an improvement in general treatment satisfaction as well as perception of hyperglycemia with respect to prior antidiabetic treatment.