Abstract 8667: Carvedilol Suppresses the Structural Remodeling in the Canine Atrial Fibrillation Model via the Suppression of Periostin as a Mediator of the Extracellular Matrix Synthesis

Background: Periostin is a novel extracellular matrix (ECM) protein, secreted from cardiac fibroblasts, and is considered to be related with cardiac fibrosis and remodeling as one of the mediators ...