The Role of CETP Modulation and Inhibition in the Progression of Coronary Heart Disease

Dr. Michael Davidson from the University of Chicago Medical Center moderated the topic "The Role of CETP Modulation and Inhibition in the Progression of Coronary Heart Disease." with Drs. Christie Ballantyne from the Baylor College of Medicine, Stephen Nicholls from the Cleveland Clinic, and Robert S. Rosenson from the Mount Sinai Hospital Medical Center. The discussion focused primarily on: (1) how CETP inhibitors/modulators modify HDL cholesterol levels; (2) the role of CETP inhibitors in dyslipidemia; (3) CETP modulation compared to inhibition; (4) HDL particle concentration compared to HDL cholesterol; (5) why did torcetrapib increase cardiovascular and total mortality; (6) newer CETP inhibitors in development and how they differ from torcetrapib (Med Roundtable Cardiovasc Ed. 2012;3(1):38-44) ©2012 FoxP2 Media, LLC