Study on In vitro Release and Transdermal Behaviors of Mumps Cataplasm of Complex Prescription

Objective:To investigate the in vitro release and transdermal behaviors of mumps cataplasm of complex prescription.Methods:The improved Franz difficusion was used and the concentration of drugs was detected.DCS was determined by HPLC and flavanoid contents were determined by UV.Results:The acumulation skin permeation percentage of DCS and flavanoid was 32% and 21%,respectively,the in vitro release percentage of DCS and flavanoid was 47% and 42%,respectively.Conclusion:The transdermal behavior of mumps cataplasm of complex prescription is an zero-order kinetics progress.The in vitro release behavior is in accordance with the Higuchi equation.