THE EFFECTS OF DISTAL CORONARY EMBOLIZATION ON INFARCT SIZE AND CARDIAC REMODELING IN A PORCINE ACUTE MYOCARDIAL INFARCTION MODEL

s S59 implantation attenuated the decline of fractional shortening after MI and the scar was significantly thicker in both BMMC groups compared to the media injected controls (p<0.05). However, ventricular function was consistently better in the BMMC-Y than the BMMC-O group after MI (p<0.05). CONCLUSION: After MI, BMMC transplantation induced a more robust inflammatory and regenerative cell response and cytokine release than the media injected controls. However, BMMC implantation did not completely restore the regenerative defects in aged mice. Although important for infarct healing, mast cell implantation did not restore youthful regeneration to old mice after an MI. 009 THE EFFECTS OF DISTAL CORONARY EMBOLIZATION ON INFARCT SIZE AND CARDIAC REMODELING IN A PORCINE ACUTE MYOCARDIAL INFARCTION MODEL RM Thomas, S Lim, B Qiang, A Osherov, NR Ghugre, H Noyan, X Qi, R Wolff, M Ladouceur-Wodzak, T Berk, J Butany, M Husain, GA Wright, BH Strauss