Abstract 16086: Simvastatin Treatment Inhibits Hypoxia Inducible Factor 1-Alpha-(Hif-1Alpha)-Prolyl-4-Hydroxylase 3 (phd-3) and Increases Angiogenesis in Streptozotocin-Induced Diabetic Rat Myocardium

Mahesh Thirunavukkarasu,Lijun Zhan,Ram Sudheer Adluri,Juan A. Sanchez,Nilanjana Maulik

Abstract 16086: Simvastatin Treatment Inhibits Hypoxia Inducible Factor 1-Alpha-(Hif-1Alpha)-Prolyl-4-Hydroxylase 3 (phd-3) and Increases Angiogenesis in Streptozotocin-Induced Diabetic Rat Myocardium

2011

Mahesh Thirunavukkarasu
Lijun Zhan
Ram Sudheer Adluri
Juan A. Sanchez
Nilanjana Maulik

Statins (HMG-CoA reductase inhibitors), are known to improve cardiac function in diabetes-induced cardiovascular disease as a result of their antioxidant capacities. Oxidative stress plays a key ro...

Keywords:

HIF-1alpha
Cardiology
Angiogenesis
Simvastatin
Internal medicine
Streptozotocin
Diabetes mellitus
Medicine
Pharmacology
Hypoxia-Inducible Factor 1-Alpha
diabetic rat

Correction
Cite
Save
Machine Reading By IdeaReader

References

Citations