Development and Evaluation of Supplementary Sheet for Preparation of Anticancer Agents-Work Sheets to Support Pharmaceutical Management Developed for Outpatient Cancer Chemotherapy-

Although calculations for the mixing of anticancer drugs are very complicated,they have been done manually by pharmacists in many institutions up to now.To address this issue,we have developed an“Information Sheet for Anticancer Drugs”,which lists the information necessary for mixing,and a“Supplementary Sheet for Mixing of Anticancer Drugs”,that enables calculations to be made automatically when checking doses.To evaluate the utility of the supplementary sheet,we conducted a questionnaire survey of staff who prepare injections for chemotherapy,such as pharmacists,nurses and physicians.In the section of the questionnaire entitled“patient information”,73.6% of the respondents said that they could calculate the dose automatically by inputting the height and weight of the patient.In the“planning of pharmacotherapy”section,67.0 % noted the simplicity of regimen confirmation and in“instructions for preparation”,74.7% stated that they could calculate doses accurately and quickly.Overall,96.7% of the respondents evaluated the supplementary sheet as useful.Our findings suggested that the supplementary sheet would be highly useful in the mixing of anticancer drugs and contribute to risk management.Further,since it can be easily adapted to the circumstances of individual institutions,it should be an extremely convenient tool for pharmacists,nurses,physicians and other medical staff.