Metabolic Tumor Volume as a Prognostic Factor for Oral Cavity Cancer Treated with Primary Surgery

Objectives:Metabolic tumor volume (MTV) obtained from pretreatment 18F-fluorodeoxydeglucose positron emission tomography with computed tomography (PET-CT) has been validated as an independent predictive factor of outcomes in head and neck cancer patients (HNC) treated with primary chemoradiotherapy (CRT). However, its role in patients treated with primary surgery has not yet been studied. The aim of the study was to evaluate the prognostic value of MTV in patients treated with primary surgery for oral cavity squamous cell carcinoma (OCSCC).Methods:Demographic and survival data were obtained from patients diagnosed with OCSCC from 2008 to 2012 in Alberta, Canada. All patients included in the study had positron emission tomography–computed tomography (PET-CT) scan before curative surgical resection. MTV and maximum standardized uptake value (SUVmax) was delineated from pretreatment PET-CT scans using Segami Oasis software (Columbus, OH).Results:A total of 80 patients were analyzed using SPSS (SPSS Inc, Chic...