NO ASSOCIATION OF PARAOXONASE-1 Q192R AND THROMBOTIC EVENTS DURING DUAL ANTI-PLATELET THERAPY IN PATIENTS AFTER ACUTE MYOCARDIAL INFARCTION

Platelet inhibition during clopidogrel treatment is known to be influenced by genetic variation, especially by reduced function alleles of cytochrome P450 (CYP) 2C19. However, recent data suggests that paraoxonase-1 (PON1) Q192R, and not CYP2C19, is the major contributor to the variability in