Is retinal microvascular damage an early manifestation of systemic sclerosis

We read with great interest the paper by Rothe et al , recently published on Annals of the Rheumatic Diseases,1 who provided evidence that patients affected with systemic sclerosis (SSc) had impaired retinal microvascular perfusion, despite the lack of ocular symptoms. Angiograms of the full retina were obtained by optical coherent tomography (OCTA) in 12 patients with SSc with established disease and 12 matched healthy subjects in a case-control cross-sectional …