Numerical simulation of process of osteoporosis in women

[Objective] The process of osteoporosis in women is studied.[Methods] Anisotropic bone modeling model with mechanostat combining with finite element method are applied.[Results] The results show that bone mass declines slowly at the beginning,loss of bone mass accelerates in postmenopause and bone mass declines 25.84%~28.63% at the age of 60 and 38.50%~40.44% at the age of 80.The result above is basically consistent with clinic result.[Conclusions] The decline of mechanical usage is primary factor leading to osteoporosis,and the menopause quickens the process of osteoporosis in women.The paper instructs the prevention and cure of osteoporosis in women clinically.