Glucose-6-Phosphate Dehydrogenase Deficiency and Type 2 Diabetes

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common X-linked human enzyme defect (1). There are a few reports that link G6PD deficiency to diabetes (2–4). We undertook a cross-sectional study at Maccabi Healthcare Services, an Israeli HMO serving two million members. All interactions and information are captured on an electronic medical record. Our study population included all male members aged ≥25 years who were tested for G6PD between 2003 and 2010 and were found positive (a quantitative …