Clinical effect of surgical resection combined with single-stage preperitoneal mesh repair for abdominal desmoid fibromatosis

Objective To investigate the clinical effect of surgical resection combined with single-stage preperitoneal mesh repair for abdominal desmoid fibromatosis. Methods The retrospective cross-sectional study was conducted. The clinical data of 19 patients with abdominal desmoid tumor who were admitted to the West China Hospital of Sichuan University from April 2005 to July 2018 were collected. Observation indicators: (1) surgical and postoperative situations: postoperative complications, tumor size, pathological type and duration of hospital stay; (2) follow-up situation: Radiochemotherapy and long-term complications of abdominal desmoid fibromatosis. Follow-up using telephone interview, outpatient examination and inpatient examination was performed to detect the recurrence and long-term complications for 12 months up to July 2019. Results All patients received surgical resection combined with single-stage preperitoneal mesh repair and were successfully followed up for 12 months, without radiochemotherapy. 4 cases showed positive expression of β-catenin. The positive expressions of SMA were showed in 3 patients. One case showed positive expression of Desmin. The duration of hospital stay was 14.8 (9 to22) days. There was no recurrence and long-term complications. Conclusion Abdominal desmoid fibromatosis is a kind of borderline tumor which can be treated as benign tumor. Surgical resections are recommended for patients with abdominal desmoid fibromatosis. Large surgical margin, frozen section and negative margin are the key points during the operation. The defect of abdominal wall should be reconstructed. Key words: Abdominal desmoid tumors; Surgery; Reconstruction of abdominal wall