Lung ultrasound score to monitor non-invasive respiratory support in hypoxemic patients

Background: lung ultrasound(LUS) score allows reliable quantification of loss of aeration[1] and was applied to monitor lung aeration[2]. Aims: To determine if LUS score early identifies responders to non-invasive respiratory support. Methods: prospective observational multicenter study. Hypoxemic patients(PaO2/FiO2 Results: 18 enrolled supports in 16 patients (males 7, age 71.5[62.5-73.5]year-old, BMI 25.6[24.2-29.8]kg/m2, SAPS2 38.5[29.0-48.0]) admitted to ICU for respiratory failure(7), abdominal(4) and vascular(2) surgery, neurological issues(2), HELLP syndrome(1). They required non-invasive support for weaning failure(6), community-acquired pneumonia(4), cardiogenic edema(3), aspiration pneumonia(3). The support was delivered by helmet CPAP(83.3%) and HFNC(16.7%); 4 were non-responders(22.2%). LUS score, PaO2/FiO2 and respiratory rate(RR) before(T0) and after 2hours(T1) of treatment are in Tab1. LUS score and PaO2/FiO2 after 2 hours predicted respiratory support failure with AUC 0.875 and 0.750 respectively. Conclusions: LUS score may early identify responders to non-invasive respiratory support. References: 1. Chiumello D., Crit Care Med 2018 2. Mojoli F., Am J Resp Crit Care Med 2018