Prognostic value of osteopontin in patients with hepatocellular carcinoma: A systematic review and meta-analysis

AbstractPurpose:The prognostic value of tissue and serum osteopontin (OPN) in hepatocellular carcinoma (HCC) remain controversial. The aim of present meta-analysis was to evaluate the prognostic value of OPN in patients with HCC.Methods:Eligible studies were systematically searched by PubMed, EMBASE