Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain

Yuanyuan Yang,Yisa Shi,Juan Jia,Shenghong Wang,Hong Chang,Mingguo Li,Xu Jin,Jing Wang

Propentofylline reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatase-1: An experimental study in a rat model of acute incisional pain

2019

Yuanyuan Yang
Yisa Shi
Juan Jia
Shenghong Wang
Hong Chang
Mingguo Li
Xu Jin
Jing Wang

ABSTRACTBackground: Acute postoperative pain can lead to long hospital stays, dysfunction, and even chronic pain. Mitogen-activated protein kinases (MAPKs) are important in pain signaling. The acti...

Keywords:

Incisional pain
Chronic pain
Phosphatase
Medicine
Diabetes mellitus
Propentofylline
Kinase
Anesthesia
Mitogen-activated protein kinase
Neuroglia
Pharmacology

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