Synchronous occurrence of gastrointestinal stromal tumour and ovarian neoplasm in a patient presenting with acute cholecystitis.

Gastrointestinal stromal tumours (GIST) are the most common mesenchymal neoplasms of the gastrointestinal (GI) tract, but account for only 0.1–3% of all GI malignancies [1]. They typically present in older individuals with a peak incidence around 60–70 years old and there is a slight male preponderance [2, 3]. GISTs can arise anywhere along the GI tract and therefore exhibit a broad spectrum of clinical symptoms. The synchronous occurrence of GISTs and other primary neoplasms is fairly common and studies have reported a prevalence between 10% and 26% [4–8]. Colorectal, oesophageal, and gastric carcinomas are frequently associated tumours [5, 7, 8]. However, the occurrence of GISTs with non-GI neoplasms, such as gynaecological tumours, is a rare phenomenon [9]. We report the case of an elderly woman who presented with acute cholecystitis and was incidentally found to have multiple intra-abdominal pathologies (gastric GIST, ovarian serous cystadenofibroma, and splenomegaly). To the best of our knowledge, this is the first reported case describing the synchronous occurrence of these two histologically distinct neoplasms. Case Presentation