Correlation study of chronic obstructive pulmonary disease patients outcomes and quality of life

Objective To provide direct interventions for patients with chronic obstructive pulmonary disease (COPD) and relevant bases of medical decision-making and resource allocation for the government by investigation of those biology-psychology-social factors which influence COPD patients medical behaviors. Methods COPD patients were followed in July in 2014 with general conditions, severity grading and questionnaire of quality of life (QOL). Telephoned patients every month, processed the health education every six months and recorded their attendance times and their compliance status.The study ended in December 2015.The final QOL questionnaire investigation was proceeded and those objects were divided into different groups according their outcomes: aggravating group, illness group without change, improved group.Multinomial Logistic regression were used to find those biological-psychological-social factors that influenced these COPD patients′ diagnosis and outcome.Variance analysis were used in groups or between-group to find out the relationship between prognosis and QOL. Results Patients with reimbursement proportion 70% higher, better compliance with health education, no complications, illness lighter (A/B) in the beginning would get better than the others (OR: 10.35 vs 2.147 vs 5.791 vs 1.51, P<0.05). Scores of aggravating group patients in the physiological, psychological and environmental area of QOL were significantly lower at the end of the study than that in the beginning of study (P<0.05). Scores in psychological area of illness group without change were obviously higher at the end of the study than that in the beginning of study (P<0.05). Scores in physiological area of improved group were obviously higher at the end of the study than that in the beginning of study (P<0.05). In the beginning of the study the QOL scores in all area of improved group patients were obviously higher than that of aggravating group patients (P<0.05). Scores in social relationship and environmental area of illness group without change patients were obviously higher than that of aggravating group patients (P<0.05). At the end of the study the QOL scores in all area of both improved or illness group without change patients were obviously higher than that of aggravating group patients (P<0.05). Conclusions Reimbursement proportion 70% or higher, better compliance, no complications, illness lighter (A/B) are protective factors.Underweight or normal, frequent acute attack and lower compliance are risk factors of COPD.Patients with higher QOL scores got improved or stable conditions.The QOL scores in both illness group without change or improved group patients are higher than that in aggravating group patients. Key words: Pulmonary diseases; Obstructive; "Biology-psychology-social" medical model; Prognosis; Health education; Compliance; Quality of life