High risk of sudden death associated with a PRKAG2-related familial Wolff-Parkinson-White syndrome.
2011
Abstract Familial appearance of Wolff-Parkinson-White (WPW) syndrome is rare and displays an autosomal dominant inheritance. Here we report a Chinese kindred of WPW syndrome whose unique clinical features consist of a high risk of sudden cardiac death due to atrial fibrillation, causing a rapid antegrade conduct over the accessory pathway. The mutation in the PRKAG2 gene was identified as responsible for the familial form of WPW syndrome.
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