Intraventricular hemorrhage score and outcome after spontaneous intracerebral hemorrhage (P2.251)

Objective: To determine whether the intraventricular hemorrhage (IVH) score is associated with outcome after intracerebral hemorrhage (ICH). Background: Spontaneous ICH has a 30% mortality rate and higher morbidity rate. Presence of IVH was found in up to 45% of cases of intracerebral spontaneous hemorrhage (ICH) and is associated with worse outcome. However, the contribution of IVH volume to outcome is not completely understood. Design/Methods: A retrospective analysis was conducted on 141 consecutive supratentorial non-traumatic ICH cases admitted from 2009–2013 to a large university hospital. IVH volume was estimated using the IVH Graeb score at admission. This score ranges from 0–12 with higher scores denoting increased IVH volume. Poor outcome was defined as a modified Rankin score (mRS) of ≥4 at hospital discharge. Descriptive statistics (presented as mean±SD), analysis of the co-variance (ANCOVA) and independent sample t-test were performed using SPSS. Results were adjusted for age, ICH volume and GCS at presentation. Results: A total of 141 cases were included in the analysis. The average age was 56±14 years and 50% were male. On admission, Glasgow coma score was 11±4, ICH volume 31±37 ml and IVH score was 3.83±4. Mean mRS at discharge was 3.89±1.67. In ANCOVA, there was a significant effect of IVH score on mRS at all levels [F(12, 125)=3.2, p=0.001] after controlling for age, ICH volume and GCS at presentation. Independent sample t-test showed there was a significant difference in mRS at discharge for IVH 0–4 group (2.7±1.8) and IVH ≥5 group (5±1.1); t (139)=8.2, p Conclusions: These results indicate that an IVH score of ≥5 is associated with poor outcome after ICH. Disclosure: Dr. Trifan has nothing to disclose. Dr. Hillmann has nothing to disclose. Dr. Testai has nothing to disclose.