Accuracy of MR Imaging–estimated Proton Density Fat Fraction for Classification of Dichotomized Histologic Steatosis Grades in Nonalcoholic Fatty Liver Disease

This prospective, cross-sectional study in an independent cohort of subjects known to have or suspected of having nonalcoholic fatty liver disease helps to validate the high-specificity Nonalcoholic Steatohepatitis Clinical Research Network–derived MR imaging proton density fat fraction thresholds by using histologic steatosis grade as a reference.