Abstract P347: The Relationship Between Renal Artery Calcium and Kidney Function: the Multi-Ethnic Study of Atherosclerosis

Background: Renal Artery Calcium (RAC) has been shown to be associated with a higher odds of hypertension (HTN). The purpose of this study was to determine if the presence and extent of RAC is associated with significant differences in several measures of kidney function. Methods: We analyzed cross-sectional data from the Multi-Ethnic Study of Atherosclerosis (MESA). During MESA follow-up visits 2 and 3, a random subsample of 1226 participants underwent computed tomography (CT) of the abdomen and also had venous blood samples assayed for kidney function. RAC was the primary predictor variable and the following measures of kidney function were the outcome variables: eGFR, cystatin-C, micro and macroalbuminuria and CKD stage. CKD stage was divided into the following groups: stage 1 GFR < 90mL/min, stage 2 GFR 60-89 mL/min, stage 3A GFR 45-59 mL/min, and stage 3B GFR 30-44 mL/min. There were no study participants in the stage 4 category of GFR < 30mL/min. The analyses were adjusted for age, gender, race, hei...