Importance of sample size in clinical trials

Adequate sample size is an important issue in clinical trials. This article aimed to assess the effect of various factors on sample size and the importance of adequate sample size in clinical trials. Recent data pertinent to study objective was searched and collected from Pub-med and other sources were analysed. It was found that factors determining adequate sample size have paramount importance in assessing the accurate results, while less or more than the required sample size has many disadvantages. A researcher needs to focus on these issues while determining sample size in a clinical trial. Emphasizing and appropriate handling of all the concerned parameters related to sample size before initiating a clinical trial will improve the validity of the study.