Use of insulin in type 2 diabetes: What we learned from recent clinical trials on the benefits of early insulin initiation

The majority of people with type 2 diabetes mellitus (T2DM) require insulin therapy to maintain HbA1c levels 9% should be given early TIIT to achieve normoglycaemia within weeks, after which standard care should then be adopted. Insulin use earlier in the treatment pathway should be considered, as it reduces the risk of hypoglycaemia as well as allows -cell rest, which can help preserve -cell function. © 2014 Elsevier Masson SAS. All rights reserved.