Symptomatic reinfection of SARS-CoV-2 with spike protein variant N440K associated with immune escape.

This report describes a case of re-infection in an individual from South India characterized by whole genome sequencing of the virus isolated from both episodes. The analysis shows the presence of an immune escape variant N440K in the Spike protein in both episodes of infection. Incidentally, this variant was also found in a case of reinfection previously reported by us in a healthcare worker from North India This article is protected by copyright. All rights reserved.