Whole blood viscosity assessment in arterial hypertension: a mathematical approach

Three mathematical models for calculation of whole blood viscosity (WBV) based on data for hematocrit (Hct), plasma viscosity (PV) or alternatively total plasma protein (TP) were tested for healthy subjects and drafts with different forms of hypertension. The equation of J. P. A. Weaver and coauthors was found to give the best statistical significance in observing alterations in WBV at particular shear rate (208 s -1 ) from patient with arterial hypertension of all types studied, including the most common type of hypertension – the essential hypertension. The mathematical approach is an alternative to the expensive and arduous experimental estimation of WBV recommended worldwide as very important in evaluation of the total peripheral resistance of the ongoing systemic atherogenesis in arterial hypertension.