Abstract 13604: Integrated Area of Desaturation Index can Predict Three-Year Prognosis in Heart Failure Patients after Adaptive Servo Ventilation Therapy

Introduction: Adaptive servo ventilation (ASV) is used as a device for patients with heart failure. Previously, we reported that Integrated Area of Desaturation Index (IAD index) can estimate the efficacy of ASV therapy in acute phase. However, it is unclear that IAD index can estimate long-term prognosis after ASV therapy. Hypothesis: We hypothesize that IAD index can predict long-term prognosis after ASV therapy. Methods: The study group consisted of 57 HF patients. The mean age was 70 ± 11 years. After treating the underlying disease in the acute phase, patients were treated with ASV. To estimate short-term effects, we established the association between changes in brain natriuretic peptide ([[Unable to Display Character: ⊿]]BNP) and left ventricular ejection fraction ([[Unable to Display Character: ⊿]]LVEF). We also estimate several polysomnographic parameters including IAD index, which is new measurement for assessing the severity of sleep apnea, which is obtained by integrating nocturnal...