Stable prostacyclin improves postischaemic microcirculatory changes in hypertensive rats

Katsuji Shima,Hitoshi Umezawa,Hiroo Chigasaki,S.-H. Okuyama,H. Araki

Stable prostacyclin improves postischaemic microcirculatory changes in hypertensive rats

1995

Katsuji Shima
Hitoshi Umezawa
Hiroo Chigasaki
S.-H. Okuyama
H. Araki

The prostacyclin analogue TTC-909 is incorporated in lipid microspheres and is chemically very stable. We examined the efficacy of TTC-909 on cerebral microcirculation following focal cerebral ischaemia.

Keywords:

Hemodynamics
Ischemia
Anesthesia
Surgery
Cerebral edema
Microcirculation
Blood–brain barrier
Prostacyclin
Cerebral blood flow
Stroke
Medicine

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