Sleep Duration and Blood Glucose Control in Women With Gestational Diabetes Mellitus.

OBJECTIVE: To describe the relationship between objectively assessed sleep and blood glucose in a prospective cohort of women recently diagnosed with gestational diabetes mellitus (GDM). METHODS: Women with GDM were enrolled immediately after attending a GDM education class. All patients were recruited during their first week of attempted dietary management of GDM. They were instructed on the use of a glucometer and on the principles of a GDM diet. Women wore an actigraph and completed a sleep log for 7 consecutive days. Glucose records were compared against the objective sleep data. Linear mixed model analysis was used to estimate the association of sleep duration on morning fasting and 1-hour postprandial blood glucose concentrations. RESULTS: Thirty-seven participants provided data for 213 sleep intervals that corresponded to at least one glucose reading. Sleep duration was negatively associated with fasting and 1-hour postprandial blood glucose concentrations In analyses adjusted for age, gestational age, and body mass index, a 1-hour increase in sleep time was associated with statistically significant reductions in fasting glucose (−2.09 mg/dL, 95% confidence interval [CI] −3.98 to −0.20) as well as postprandial glucose concentrations (lunch −4.62 mg/dL, 95% CI −8.75 to −0.50; dinner −6.07 mg/dL, 95% CI −9.40 to −2.73). CONCLUSION: Short sleep durations are associated with worsened glucose control in women with gestational diabetes. Educating women on healthy sleep and screening for and treating sleep disorders during pregnancy may have a role in optimizing blood glucose control in gestational diabetes. LEVEL OF EVIDENCE: II