Atheroembolic disease (cholesterol crystal embolism)

: The atheroembolic disease, often non recognized and fatal in the elderly, is a complication of atherosclerosis characterized by obstruction of multiple small arteries by cholesterol crystals. It may occur spontaneously or after aortic wall trauma, latter usually following angiography or cardiovascular surgery, and the use of anticoagulants. Renal failure, livedo reticularis and acrocyanosis of the lower extremities have been frequently described. In some cases the clinical picture may resembling a vasculitis. The diagnosis can be confirmed by skin, muscle or kidney biopsy. In practice, the treatment is symptomatic. The most effective measure is prevention.