Minimal Residual Disease–guided Risk Restratification and Therapy Improves the Survival of Childhood Acute Lymphoblastic Leukemia

The minimal residual disease (MRD) has been shown to be very important to evaluate the prognostic significance in childhood acute lymphoblastic leukemia (ALL), but the impact under the current treatment protocol in China has not been fully elucidated. The aim of this study was to investigate the eff