Abstract 17361: An Optimized Human Apyrase Substantially Decreases Infarct Size Without Bleeding Time Prolongation after Coronary Fibrinolysis in Dogs and Coronary Ligation and Release in Mice

Introduction: Early coronary reperfusion by percutaneous coronary intervention or pharmacologic fibrinolysis attenuates myocardial infarction, but thrombotic reocclusion and reperfusion injury limi...