Cervical artery stenoses in sickle cell disease.

97.8%; A2Hb 2.2%, and AHb undetectable. Despite thrombolysis, blood transfusion exchanges, and anti-edematous treatment, the patient’s condition deteriorated. A decompressive craniectomy was performed on the 4th day. At 6 months, the patient remained hemiparetic and was unable to walk, but his dysphasia had markedly improved. The modified Ranking score was 4. Screening for thrombophilia (protein C and S, factor VII, antithrombin III and lipoprotein (a) plasma levels, search for antiphospholipid antibodies, factor V Dear Sir, Ischemic stroke is a common complication of sickle cell disease (SCD). Approximately 1 in10 patients with this disease has a stroke before the age of 20 years, and 20% have evidence of brain infarction on MRI [1–3] . It is the primary cause of stroke in children [2] . Ischemic stroke in these patients is usually associated with an intracranial internal carotid (IC) fork stenosis or occlusion. Here we report a patient with SCD, ischemic stroke and multiple stenoses of the extracranial carotid and vertebral arteries.