Double-Blind, Double-Dummy Comparative Study of Local Action Transcutaneous Flurbiprofen (Flurbiprofen LAT) versus Piketoprofen Cream in the Treatment of Extra-Articular Rheumatism

Objective A local action transcutaneous (LAT) system has been developed for the topical application of the nonsteroidal anti-inflammatory drug flurbiprofen. The purpose of the present study was to compare the efficacy and tolerability as well as the patients’ acceptance of flurbiprofen LAT versus the cream formulation of piketoprofen in the treatment of patients with soft tissue rheumatism.