Promene funkcije leve komore kod pacijenata sa hroničnim pankreatitisom koji je uzrokovan alkoholom

The aim of the study was to determine systolic and diastolic left ventricular function in the patients with chronic pancreatitis. Sixteen patients with chronic alcoholic pancreatitis (12 male and 4 female; 43+7 years old; 11 with diabetes) and 15 healthy controls ( 8 male and 7 female; 37+9 years old) were included in the study. No one had any clinical signs of heart disease. Using two-dimensional echocardiography, in patients and controls we estimated: end diastolic diameter (EDD); end systolic diameter(ESD) ejection fraction (EF) and fractionar shortening (FS). By Doppler echocardiography we measured the peak early and artrial filling velocities and their ratio as well. In patients with chronic pancreatitis systoliuc function was preserved since diastolic dysfunction was reveled (VA in patients versus VA in controls: 0,66+0,13 vs. 0,45+0,05 p<0,05; VE/VA ratio in patients versus VE/VA in controls: O,91+0,3 vs. 1,3+0,3 p<0,05). We can consider diabetes mellitus, major complication of chronic pancreatitis as the primarly cause of left ventricular diastolic dysfunction.