Drug resistance of 136 Acinetobacter baumannii strains 2006-2008.

OBJECTIVE To investigate drug resistance diversity of Acinetobacter baumannii in our hospital in recent years,thus guiding rational clinical application of antibacterials and controlling nosocomial infection.METHODS Totally 136 strains of A.baumanniis were collected from Tai′an Central Hospital from 2006 to 2008,whose drug sensitivity to 14 antibacterials including ceftazidime was detected by disk diffusion method and the susceptibility test results were analyzed.RESULTS The resistance rate of the 136 A.baumannii strains to cefoperazone/sulbactam,imipenem,meropenem,cefepime,piperacillin/tazobactam,amikacin,ceftazidime,levofloxacin,gentamicin,piperacillin,SMZ-TMP,ciprofloxacin,and ceftriaxone was 15.4%,16.2%,16.9%,44.1%,45.6%,47.8%,50.0%,57.4%,59.6%,64.0%,65.4%,77.2%,80.1% and 83.0%,respectively.CONCLUSIONS All of 136 A.baumannii strains from our hospital have low resistance to cefoperazone/sulbactam,imipenem and meropenem,and high resistance to other above-mentioned antibacterials.But their resistance to imipenem and meropenem increase year by year during the 3 years.