Antiplatelet Medications Protect Against Aortic Dissection and Rupture in Patients With Abdominal Aortic Aneurysms

The platelet phenotype may change in disease. We previously demonstrated in patients with myocardial infarction (MI) and in a murine model of MI that platelets synthesize and secrete activated matrix metalloproteinase 9. This was not observed in healthy individuals ([1][1],[2][2]). Enhanced platelet