Reassessment of tigecycline bone concentrations in volunteers undergoing elective orthopedic procedures.

Thegoalofthethisstudywastore‐evaluatetigecyclineboneconcentrationsinsubjectsundergoingelectiveorthopedicsurgery,usingmultipledosesand a more robust bone assay than was used in a previous study. Each subject received three intravenous doses of tigecycline (one 100‐mg infusion followed