108: Beam monitoring and dosimetry tools for radiobiology experiments at the cyclotron ARRONAX

The ARRONAX (Accelerateur pour la Recherche en Radiochimie et Oncologie a Nantes Atlantique) cyclotron in Saint Herblain - France is a facility delivering alpha particles at 68 MeV (1). One of its purposes is to become a platform for radiobiological studies. The radiobiological studies evolvearound two axes: the low energy range (<10MeV) in order to optimize radio-immunotherapy (RIT) treatments, and the high energy range (30-68 MeV) in order to puzzle out the fundamental mechanisms generated by cells in response to ionizing radiations.The ARRONAX platform for radiobiology is currently preparing to use a time lapse fluorescence confocal microscope suitable for the irradiation of cell wells. This platform should contain tools for beam intensity checks to enable accurate and repeatable irradiation conditions and a device to monitor thedelivered dose.