Tx ™: An Approach and Philosophy to Advance Translation to Transformation

The translational science spectrum consists of phases or types of research, from dis­coveries that advance our understanding of the biological basis of health and disease to interventions that engage individuals and social systems toward improved popula­tion health. The health research system has widely acknowledged flaws that delay (or even deny) the fruits of research findings for the population and for chronically disad­vantaged groups. Coined and patented at Morehouse School of Medicine (MSM), Tx TM symbolizes an approach and scientific philosophy that intentionally promotes and supports the convergence of interdisciplin­ary approaches and scientists to stimulate exponential advances for the health of diverse communities. While the Tx TM patent is new, this approach to research transla­tion is embedded within the MSM tapestry with historically aligned research from the Translational Collaborative Center exem­plars as well as newly funded scholars. Tx TM scholarship is characterized by the five te­nets and practices that ultimately culminate in the conduct of research with results that broaden the evidence-base through data-driven proof of impact on health equity in underserved or special populations. Tx TM is a destination that is ever-evolving and responsive to the research, priority popula­tions and partners through translational research and corresponding approaches that transform health, thereby advancing health equity. Ethn Dis. 2019;29(Suppl 2): 349- 354. doi:10.18865/ed.29.S2.349