385 Cutaneous phototoxicity secondary to ciprofloxacin in adult patients with cystic fibrosis: incidence and association with genotype

RhDNA-ase (Pulmozyme®) is used in the treatment in our patients since 1996. Currently 114 patients are on the chronic treatment with rhDNA-ase (39.5% of CF pts. on Slovak National Registry). 11 patients died in this period on respiratory or liver failure. Methods: Longterm follow-up study of 84 CF patients aged 5−48 years, treated more than 10 years. Patients were divided in three groups according to their initial FEV1 value: group A: (n = 13, mean age 17.2 yrs) with FEV1< 60% p.v. Group B (n = 23, mean age 12.6 yrs) with 60%

Keywords:

• Cystic fibrosis
• Ciprofloxacin
• FEV1/FVC ratio
• Pathology
• Medicine
• Quality of life
• Group A
• Diabetes mellitus
• Group B
• Respiratory system

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